Body size trajectories and cardio-metabolic resilience to obesity

Recently Discovered Adipokines and Cardio-Metabolic Comorbidities in Childhood Obesity

White adipose tissue (WAT) asset, in terms of cell number, fat storage capacity and endocrine function, is largely determined in early stages of life and is pivotal for shaping the WAT pro-inflammatory behavior. WAT derived adipokines have been shown to play a main role in several cardio-metabolic abnormalities of obesity. This review focuses on the most recently identified adipokines, namely a...

Field metabolic rate and body size.

The field metabolic rates (FMRs) of 229 species of terrestrial vertebrates, all measured using the doubly labeled water method in free-living individuals, were evaluated. Daily rates of energy expenditure were as low as 0.23 kJ per day in a small reptile (gecko), to as high as 52 500 kJ per day in a marine mammal (seal). This is a range of nearly six orders of magnitude. More than 70% of the va...

Obesity/Metabolic Syndrome Arterial Load and Ventricular-Arterial Coupling Physiologic Relations With Body Size and Effect of Obesity

Accurate quantification of arterial function is crucial to distinguishing disease states from normal variants. However, there are little data regarding methods to scale arterial load to body size in humans. We studied 2365 adults aged 35 to 55 years free of overt cardiovascular disease. We assessed arterial hemodynamics and ventricular-vascular coupling with carotid tonometry and Doppler echoca...

Sleep and Cardio-Metabolic Disease

PURPOSE OF REVIEW This review summarises and discusses the epidemiological evidence suggesting a causal relationship between sleep duration and cardio-metabolic risk and outcomes in population. RECENT FINDINGS Sleep duration is affected by a variety of cultural, social, psychological, behavioural, pathophysiological and environmental influences. Changes in modern society-like longer working h...

which one is more important, obesity or cardio metabolic risk factors?